Some Heterocyclic Hydrazone Compounds: Synthesis, Spectral Characterization and Anticancer Activity Study

Cancer is currently ongoing to be a significant health problem threatening human health. Hydrazone compounds constitute popular class of organic used in novel drug discovery studies therapy cancer. In the current study, preparation and structural characterization some heterocyclic hydrazone (7-12) their anticancer capacities against HeLa cervical cancer MCF-7 breast cell lines were reported. The target characterized by spectroscopic techniques (1H NMR, 13C NMR FT-IR). vitro cytotoxic potentials molecules assessed using MTT assay two lines. L929 mouse fibroblast employed as normal cell. results displayed that tested had varying activities. Among compounds, compound 8 indicated activity cells with IC50 value 34.38 µM. On other hand, these 11 (IC50 = 26.84 µM) cells.